Science Behind Low Calorie Energy Drinks Like 5-hr Energy

Latest Ask a Coach question comes from reader Pat regarding the efficacy of low calorie “energy” drinks:

Question: I recently saw some people taking a low calorie energy drink/shot like 5-hour Energy before a half marathon. Is there any science behind those high B vitamin drinks? By definition a calorie is a unit of energy, so if those drinks have little to no calories, then they can’t have much energy, right? Are they tricking our bodies into feeling more energetic?